In addition to command-line scripting of Thimbl, I have added a little GUI tool around the CLI. Here's a little screenshot showing the latest messages, and the people I'm following:
You can see it in action for yourself by checking out the latest commits from https://github.com/blippy/Thimbl-CLI . Start the GUI by typing: python gthimbl.py . It's pretty much as easy as that. Requires wxPython, though.